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Technical Insights and Legal Considerations for Advancing Federated Learning in Bioinformatics

Published: March 12, 2025 | arXiv ID: 2503.09649v2

By: Daniele Malpetti , Marco Scutari , Francesco Gualdi and more

Potential Business Impact:

Lets doctors share medical secrets safely.

Business Areas:
Bioinformatics Biotechnology, Data and Analytics, Science and Engineering

Federated learning leverages data across institutions to improve clinical discovery while complying with data-sharing restrictions and protecting patient privacy. As the evolution of biobanks in genetics and systems biology has proved, accessing more extensive and varied data pools leads to a faster and more robust exploration and translation of results. More widespread use of federated learning may have the same impact in bioinformatics, allowing access to many combinations of genotypic, phenotypic and environmental information that are undercovered or not included in existing biobanks. This paper reviews the methodological, infrastructural and legal issues that academic and clinical institutions must address before implementing it. Finally, we provide recommendations for the reliable use of federated learning and its effective translation into clinical practice.

Page Count
13 pages

Category
Quantitative Biology:
Other Quantitative Biology