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Language Models for Longitudinal Clinical Prediction

Published: October 27, 2025 | arXiv ID: 2510.23884v1

By: Tananun Songdechakraiwut, Michael Lutz

Potential Business Impact:

Helps doctors predict diseases early from patient notes.

Business Areas:
Natural Language Processing Artificial Intelligence, Data and Analytics, Software

We explore a lightweight framework that adapts frozen large language models to analyze longitudinal clinical data. The approach integrates patient history and context within the language model space to generate accurate forecasts without model fine-tuning. Applied to neuropsychological assessments, it achieves accurate and reliable performance even with minimal training data, showing promise for early-stage Alzheimer's monitoring.

Country of Origin
🇺🇸 United States

Page Count
13 pages

Category
Computer Science:
Computation and Language