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PathBench-MIL: A Comprehensive AutoML and Benchmarking Framework for Multiple Instance Learning in Histopathology

Published: December 19, 2025 | arXiv ID: 2512.17517v1

By: Siemen Brussee , Pieter A. Valkema , Jurre A. J. Weijer and more

We introduce PathBench-MIL, an open-source AutoML and benchmarking framework for multiple instance learning (MIL) in histopathology. The system automates end-to-end MIL pipeline construction, including preprocessing, feature extraction, and MIL-aggregation, and provides reproducible benchmarking of dozens of MIL models and feature extractors. PathBench-MIL integrates visualization tooling, a unified configuration system, and modular extensibility, enabling rapid experimentation and standardization across datasets and tasks. PathBench-MIL is publicly available at https://github.com/Sbrussee/PathBench-MIL

Category
Computer Science:
CV and Pattern Recognition